Mirella Santos

Dr. Mirella P. Santos

Senior Plant Cell and Molecular Biologist (Visiting Scientist)


  • D.Sc., Plant Genetic Improvement, North Fluminense State University (UENF), Campos, Rio de Janeiro.  
  • M.S., Plant Biology, Espirito Santo Federal University, Vitoria, Espirito Santo, Brazil.  

Work History: 

  • Bio Huma Netics, Inc. (2022) 
  • Rio de Janeiro Federal University, Brazil (2015) 

I’m from Brazil and married to Dr. Daniel Zandonadi. I have an extensive research background in plant genomic and plant transformation. At Rio de Janeiro Federal University, Brazil, I was responsible for administrative and technical supervision of scientific and technical staff to evaluate plant stress mitigation by humic and nanocarbon products from private companies through public-private partnerships (UFRJ and companies). I’m a visiting scientist at Huma and love collaborating with fellow scientists on various projects.   


Original Articles 

 Santos, M. P., dos Santos Prado, L. A., Cogo, A. J. D., Lopes, A. V. S. A., Caldeira, C. F., Cavalcante, A. B., … & Zandonadi, D. B. (2022). High irradiance impairs Isoëtes cangae growth. Aquatic Botany, 103590.  



Citadin, C. T., Santos, M. P., Andrade, E. R., Cipriano, T. M., & Aragão, F. J. (2022). Colorimetric and chlorophyll fluorescence assays for fast detection and selection of transgenic events of cotton, cowpea, soybean and common bean expressing the Atahas gene. Plant Breeding and Biotechnology, v. 10, p. 94-101, 2022. 



do Rego, T.F.C., Santos, M.P., Cabral, G.B. et al. (2021). Expression of a DREB 5-A subgroup transcription factor gene from Ricinus communis (RcDREB1) enhanced growth, drought tolerance and pollen viability in tobacco. Plant Cell Tiss Organ Cult 146, 493–504. 



Caldeira, C. F., Lopes, A. V., Aguiar, K. C., Ferreira, A. L., Araujo, J. V., Gomes, V. M., … & Santos, M. P. (2021). Distinct Reproductive Strategy of Two Endemic Amazonian Quillworts. Diversity, 13(8), 348.  



Souza, A. C., Zandonadi, D. B., Santos, M. P., Canellas, N. O. A., de Paula Soares, C., da Silva Irineu, L. E. S., … & Canellas, L. P. (2021). Acclimation with humic acids enhances maize and tomato tolerance to salinity. Chemical and Biological Technologies in Agriculture, 8(1), 1-13. 



Cavalheiro-Filho, S. L., Gestinari, L. M., Konno, T. U., Santos, M. P., Calderon, E. N., Marques, M. C., … & Campos, N. V. (2021). Morphological Plasticity in the Endemic Isoëtes Species from Serra dos Carajás, Amazonia, Brazil. American Fern Journal, 111(3), 174-195. 



Dalapicolla, J., Alves, R., Jaffé, R., Vasconcelos, S., Pires, E. S., Nunes, G. L., … & Oliveira, G. (2021). Conservation implications of genetic structure in the narrowest endemic quillwort from the Eastern Amazon. Ecology and evolution, 11(15), 10119-10132. 



dos Santos Pereira, T., Monteiro de Paula, A., Ferrari, L. H., da Silva, J., Borges Pinheiro, J., Navas Cajamarca, S. M., … & Busato, J. G. (2021). Trichoderma-enriched vermicompost extracts reduces nematode biotic stress in tomato and bell pepper crops. Agronomy, 11(8), 1655. 



Zandonadi, D. B., Duarte, H. M., Santos, M. P., dos Santos Prado, L. A., Martins, R. L., Calderon, E. N., … & de Assis Esteves, F. (2021). Ecophysiology of two endemic Amazon quillworts. Aquatic Botany, 170, 103350. 



Santos, M. P., Zandonadi, D. B., de Sá, A. F. L., Costa, E. P., de Oliveira, C. J. L., Perez, L. E., … & Bressan-Smith, R. (2020). Abscisic acid-nitric oxide and auxin interaction modulates salt stress response in tomato roots. Theoretical and Experimental Plant Physiology, 32(4), 301-313. 



Santos, M. P., Araujo, J. V. R., Lopes, A. V. S. A., Vettorazzi, J. C. F., Boechat, M. S. B., Arêdes, F. A., … & de Assis Esteves, F. (2020). The genetic diversity and population structure of two endemic Amazonian quillwort (Isoetes L.) species. PeerJ, 8, e10274. 



Vieira, P. M., Santos, M. P., Andrade, C. M., Souza-Neto, O. A., Ulhoa, C. J., & Aragão, F. J. L. (2017). Overexpression of an aquaglyceroporin gene from Trichoderma harzianum improves water-use efficiency and drought tolerance in Nicotiana tabacum. Plant Physiology And Biochemistry, 121, 38-47. 



Zandonadi, D. B., Santos, M. P., Caixeta, L. S., Marinho, E. B., Peres, L. E. P., & Façanha, A. R. (2016). Plant proton pumps as markers of biostimulant action. Scientia Agricola, 73(1), 24-28. 



Zandonadi, D. B., Santos, M. P., Medici, L. O., & Silva, J. (2014). Action of organic matter and its fractions on vegetables physiology. Horticultura Brasileira, 32(1), 14-20. 



Paez-Valencia, J., Sanchez, J., Marsh, E., Dorneles, L. T., Santos, M. P., Sanchez, D., … & Gaxiola, R. (2013). Enhanced H+-PPase activity improves nitrogen use efficiency in Romaine lettuce (Lactuca sativa cv. conquistador). Plant Physiology. 



Zandonadi, D. B., Santos, M. P., Busato, J. G., Peres, L. E. P., & Façanha, A. R. (2013). Plant physiology as affected by humified organic matter. Theoretical and Experimental Plant Physiology, 25(1), 13-25. 



Undurraga, S. F., Santos, M. P., Paez-Valencia, J., Yang, H., Hepler, P. K., Facanha, A. R., … & Gaxiola, R. A. (2012). Arabidopsis sodium dependent and independent phenotypes triggered by H+-PPase up-regulation are SOS1 dependent. Plant Science, 183, 96-105. 



Shaun Buss, D., Bueno Dias, G., Pupo Santos, M., Aires Ventura, J., & Machado Bueno Fernandes, P. (2011). Oxidative stress defence response of Carica papaya challenged by nitric oxide, Papaya meleira virus and Saccharomyces cerevisiae. The Open Nitric Oxide Journal, 3(1). 



Zandonadi, D. B., Santos, M. P., Dobbss, L. B., Olivares, F. L., Canellas, L. P., Binzel, M. L., … & Façanha, A. R. (2010). Nitric oxide mediates humic acids-induced root development and plasma membrane H+-ATPase activation. Planta, 231(5), 1025-1036. 



Fontes, R. V., Santos, M. P., Falqueto, A. R., Silva, D. M., & Bacarin, M. A. (2008). Photosynthesis and growth changes in papaya plants under different water supply conditions. Revista Brasileira Agrociência, 14, 182-187. 



Martim, S. A., Santos, M. P., Peçanha, A. L., Pommer, C., Campostrini, E., Viana, A. P., … & Bressan-Smith, R. (2009). Photosynthesis and cell respiration modulated by water deficit in grapevine (Vitis vinifera L.) cv. Cabernet Sauvignon. Brazilian Journal of Plant Physiology, 21(2), 95-102. 



Garcia, R., Alves, E. S., Santos, M. P., Aquije, G. M., Fernandes, A. A. R., Santos, R. B. D., … & Fernandes, P. (2008). Antimicrobial activity and potential use of monoterpenes as tropical fruits preservatives. Brazilian Journal of Microbiology, 39(1), 163-168. 



Fontes, R. V., Santos, M. P., Falqueto, A. R., & Silva, D. M. (2008). The pectinmethylesterase activity and its relation with the loss of firmness of the pulp in papaya fruits cv. Sunrise solo and Tainung. Revista Brasileira de Fruticultura, 30(1), 54-58. 



Fontes, R. V., Santos, M. P., Falqueto, A. R., & Silva, D. M. (2008). Nitrate reductase activity and chlorophyll a fluorescence in papaya. Revista Brasileira de Fruticultura, 30(1), 251-254. 



Book Chapters  

Zandonadi DB, Santos MP, Olivares FL, Canellas LP. 2022. Humic acids and fatty acid amides: soil-plant interactions. In: Strigolactones, Karrikins and Alkamides in Plants. Taylor and Francis, USA (“in press”). 


Santos, Mirella Pupo. A importancia dos fatores de mendel: aspectos genéticos, moleculares e fisiológicos relacionados ao estresse abiótico. Mendel: das leis da hereditariedade `a engenharia genética. 220ed.Brasilia: Embrapa, 2017, v. , p. 150-169. 


Fernandes, P.M.B., Santos, M.P., Ventura, J. A. Indução de resposta a estresse em mamoeiro após tratamento com levedura e óxido nítrico. Papaya Brasil: mercado e inovações tecnológicas para o mamão, edited by David dos Santos Martins. 231-234. Vitória: Incaper. 2005. 


Falqueto, A.R., Santos, M.P., Alves, E.S.S., Silva, D.M. Respostas fotossintéticas de Carica papaya L. à infecção fúngica. Qualidade do Mamão Para o Mercado Interno, edited by: David dos Santos Martins; Helder Paulo Carnielli; Pedro de Faria Burnier. (Org.). Papaya Brasil. ed 1. Vol. 1, 427-429. Vitoria-ES: DCM 2003. 


Marques, S.S, Santos, M.P., Alves, E.S.S., Thabita T.D.V., Santos, R. B., Ventura, J.A., Fernandes, P.M.B. uso de óleos essenciais no controle de Colletotrichum gloeosporioides, In: Papaya Brasil: qualidade do mamão para o mercado interno, edited by: David dos Santos Martins. Vol. 591-593. Vitória: Incaper, 2003.